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| カタログ番号 | MV297014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse CD84/SLAMF5 Polyclonal Antibody (MV297014) is a rabbit polyclonal antibody detecting CD84/SLAMF5 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD84 (Met27-Gln206). | ||||||||
| ターゲット | SLAM family member 5 (Leukocyte differentiation antigen CD84) (Signaling lymphocytic activation molecule 5) (CD antigen CD84) | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q18PI6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | SLAM family member 5 (CD84) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. 1. Wang, N. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 5683-7. PMID: 20962259 2. Cannons, JL. et al. (2010) Immunity 32, 253-65. PMID: 20153220 3. Wong, EB. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 4130-43. PMID: 25801429 4. Sintes, J. et al. (2010) Journal of leukocyte biology 88, 687-97. PMID: 20628063 | ||||||||
| 注意事項 | For research use only. |
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