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Anti-Mouse CD8 alpha Recombinant Antibody (YTS105.18), APC (MF815237)

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Vista general
Número de catálogoMF815237
Reactividad de especiesMouse
AplicacionesFCM
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonYTS105.18
ConjugaciónAPC
Objetivo CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Productos asociados Rat IgG2a, kappa Recombinant Isotype Control Antibody (RTK2758), APC
Número de acceso P01731
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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