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Anti-Mouse CD8 alpha Recombinant Antibody (YTS105.18), PE (MF815227)

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概要
カタログ番号MF815227
種反応性Mouse
アプリケーションFCM
宿主種Rat
クローン性Monoclonal
アイソタイプIgG2a, kappa
クローンIDYTS105.18
抱合PE
ターゲット CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
関連製品 Rat IgG2a, kappa Recombinant Isotype Control Antibody (RTK2758), PE
アクセッション番号 P01731
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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参考文献
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