Anti-Mouse CD8B//Lyt3 Recombinant Antibody (YTS156.7.7), PE (MY433127)

Name: Anti-Mouse CD8B//Lyt3 Recombinant Antibody (YTS156.7.7), PE
Brand: abinScience
SKU: MY433127
Price: 256 USD
Availability: InStock

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Número de catálogo	MY433127
Reactividad de especies	Mouse
Aplicaciones	FCM
Especie huésped	Rat
Clonalidad	Monoclonal
Isotipo	IgG2b, kappa
ID de clon	YTS156.7.7
Conjugación	PE
Objetivo	T-cell surface glycoprotein CD8 beta chain, Lymphocyte antigen 3, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein Lyt-3, CD8b, Cd8b1, Ly-3, Lyt-3, Lyt3, cd8
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Rat IgG2b, kappa Recombinant Isotype Control Antibody (ES26-5E12.4), PE
Número de acceso	P10300
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	T-cell surface glycoprotein CD8 beta chain (CD8b/Lyt3) is a ~24 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Flow Cytometry

Flow-cytometry using PE anti-Mouse CD8b antibody. Mouse spleen cells were stained with an irrelevant antibody (Green Histogram) or a PE anti-Mouse CD8b antibody monoclonal antibody (Catalog # MY433127 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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