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Anti-Mouse Fas/TNFRSF6/CD95 Recombinant Antibody (HFE7A), FITC (MB873117)

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Vista general
Número de catálogoMB873117
Reactividad de especiesHuman, Mouse
AplicacionesELISA, FCM, WB
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonHFE7A
ConjugaciónFITC
Objetivo Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, Fas, Apt1, Tnfrsf6
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), FITC
Número de acceso P25446
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

Tumor necrosis factor receptor superfamily member 6 (CD95/FAS) is a ~37 kDa protein. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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