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Anti-Mouse Fas/TNFRSF6/CD95 Recombinant Antibody (HFE7A), FITC (MB873117)

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Aperçu
Numéro de catalogueMB873117
Reactivité des espècesHuman, Mouse
ApplicationsELISA, FCM, WB
Espèce hôteRat
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneHFE7A
ConjugaisonFITC
Cible Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, Fas, Apt1, Tnfrsf6
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), FITC
Numéro d'accès P25446
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Tumor necrosis factor receptor superfamily member 6 (CD95/FAS) is a ~37 kDa protein. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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