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| カタログ番号 | MC339014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse CDw210b/IL10RB Polyclonal Antibody (MC339014) is a rabbit polyclonal antibody detecting CDw210b. Suitable for Mouse.
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CDw210b/IL10RB (Met20-Asn214). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | CDw210b, CRF2-4, CRFB4, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, D21S58, D21S66, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10R2, IL-10RB, IL10RB, Interleukin-10 receptor subunit 2, Interleukin-10 receptor subunit beta | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q61190 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Interleukin-10 receptor subunit beta (CDw210b/IL10RB) is a ~39 kDa protein. Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. | ||||||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-IL10RB polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat heart lysate
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