

| Numéro de catalogue | MA375014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse CHST3 Polyclonal Antibody (MA375014) is a rabbit polyclonal antibody detecting CHST3 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse CHST3 (Arg127-Thr472). | ||||||||
| Cible | GST-0, C6ST-1, Chondroitin 6-O-sulfotransferase 1, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0, CHST3, Carbohydrate sulfotransferase 3, Chondroitin 6-sulfotransferase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O88199 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Carbohydrate sulfotransferase 3 (CHST3) is a ~53 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Catalyzes with a lower efficiency the sulfation of Gal residues of keratan sulfate, another glycosaminoglycan. Can also catalyze the sulfation of the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen. 1. Uchimura, K. et al. (2002) The Journal of biological chemistry 277, 1443-50. PMID: 11696535 2. Uchimura, K. et al. (1998) Glycobiology 8, 489-96. PMID: 9597547 | ||||||||
| Note | For research use only. |
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