



| Numéro de catalogue | MW810013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Mouse, Rat | ||||
| Applications | ELISA, IHC | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG1 | ||||
| ID de clone | 15A11 | ||||
| Cible | TSP5, Thrombospondin-5, COMP, Cartilage oligomeric matrix protein | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q9R0G6 | ||||
| RRID | Anti-Mouse COMP Antibody (15A11) (abinScience Cat# MW810013, RRID:AB_3725643) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Cartilage oligomeric matrix protein (COMP) is a ~82 kDa protein. Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). 1. Li, C. et al. (2020) Nature communications 11, 3642. PMID: 32686688 | ||||
| Note | For research use only. |

SEC-HPLC detection for Anti-Mouse COMP Antibody (15A11).

SDS-PAGE for Anti-Mouse COMP Antibody (15A11).
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