



| Каталожный номер | MW810013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Mouse, Rat | ||||
| Применения | ELISA, IHC | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG1 | ||||
| ID клона | 15A11 | ||||
| Цель | TSP5, Thrombospondin-5, COMP, Cartilage oligomeric matrix protein | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q9R0G6 | ||||
| RRID | Anti-Mouse COMP Antibody (15A11) (abinScience Cat# MW810013, RRID:AB_3725643) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Cartilage oligomeric matrix protein (COMP) is a ~82 kDa protein. Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). 1. Li, C. et al. (2020) Nature communications 11, 3642. PMID: 32686688 | ||||
| Примечание | For research use only. |

SEC-HPLC detection for Anti-Mouse COMP Antibody (15A11).

SDS-PAGE for Anti-Mouse COMP Antibody (15A11).
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