Anti-Mouse CXCL12/SDF-1 Recombinant Antibody (30D8) (MW376013)

Name: Anti-Mouse CXCL12/SDF-1 Recombinant Antibody (30D8)
Brand: abinScience
SKU: MW376013
Price: 110 USD
Availability: InStock

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Prix(USD) :

Spécification :

20ug
50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MW376013

Reactivité des espèces

Human, Mouse

Applications

ELISA, FCM

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

30D8

Cible

Intercrine reduced in hepatomas, hSDF-1, Stromal cell-derived factor 1, SDF-1, Pre-B cell growth-stimulating factor, SDF1, SDF1A, C-X-C motif chemokine 12, SDF1B, CXCL12, IRH, PBSF, hIRH

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P40224

RRID

Anti-Mouse CXCL12/SDF-1 Antibody (30D8) (abinScience Cat# MW376013, RRID:AB_3725651)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Stromal cell-derived factor 1 (CXCL12/SDF-1) is a ~10 kDa protein. Chemoattractant active on T-lymphocytes and monocytes but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for CXCL12/SDF-1. Binds to the allosteric site (site 2) of integrins and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 in a CXCR4-independent manner. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase.

1. Nagasawa, T. et al. (1996) Nature 382, 635-8. PMID: 8757135

2. Nagasawa, T. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 2305-9. PMID: 8134392

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse CXCL12/SDF-1 Antibody (30D8).
Western blot

Western blot analysis was performed using anti-human CXCL12/SDF-1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CXCL12/SDF-1 (Catalog No: HW376012)
Lane 2: negative control

Reférences

Fiche technique

Anti-Mouse CXCL12/SDF-1 Recombinant Antibody (30D8).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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