Anti-Mouse CXCL12/SDF-1 Recombinant Antibody (30D8) (MW376013)

Name: Anti-Mouse CXCL12/SDF-1 Recombinant Antibody (30D8)
Brand: abinScience
SKU: MW376013
Price: 110 USD
Availability: InStock

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Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

MW376013

Реактивность видов

Human, Mouse

Применения

ELISA, FCM

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG1, kappa

ID клона

30D8

Цель

Intercrine reduced in hepatomas, hSDF-1, Stromal cell-derived factor 1, SDF-1, Pre-B cell growth-stimulating factor, SDF1, SDF1A, C-X-C motif chemokine 12, SDF1B, CXCL12, IRH, PBSF, hIRH

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P40224

RRID

Anti-Mouse CXCL12/SDF-1 Antibody (30D8) (abinScience Cat# MW376013, RRID:AB_3725651)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Stromal cell-derived factor 1 (CXCL12/SDF-1) is a ~10 kDa protein. Chemoattractant active on T-lymphocytes and monocytes but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for CXCL12/SDF-1. Binds to the allosteric site (site 2) of integrins and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 in a CXCR4-independent manner. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase.

1. Nagasawa, T. et al. (1996) Nature 382, 635-8. PMID: 8757135

2. Nagasawa, T. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 2305-9. PMID: 8134392

Примечание

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Изображения

SDS-PAGE

SDS-PAGE for Anti-Mouse CXCL12/SDF-1 Antibody (30D8).
Western blot

Western blot analysis was performed using anti-human CXCL12/SDF-1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CXCL12/SDF-1 (Catalog No: HW376012)
Lane 2: negative control

Ссылки

Даташит

Anti-Mouse CXCL12/SDF-1 Recombinant Antibody (30D8).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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