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| カタログ番号 | MV571147 |
|---|---|
| 種反応性 | Human, Mouse, Monkey |
| アプリケーション | ELISA, FCM |
| 宿主種 | Rat |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | 21H3RK |
| 抱合 | PerCP |
| ターゲット | Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), PerCP |
| アクセッション番号 | Q9JI71 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. 1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954 2. Luo, H. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, E553-62. PMID: 22323600 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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