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| カタログ番号 | MV571014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse DLL4 Polyclonal Antibody (MV571014) is a rabbit polyclonal antibody detecting DLL4 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse DLL4 (Gly27-Ser177). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9JI71 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. 1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954 2. Luo, H. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, E553-62. PMID: 22323600 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-DLL4 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat lung lysate
Lane 2: Rat kidney lysate
Lane 3: Rat pancears lysate
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