

| Numéro de catalogue | MP294014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse EGFLAM Polyclonal Antibody (MP294014) is a rabbit polyclonal antibody detecting EGFLAM in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
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| Reactivité des espèces | Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse EGFLAM (Asp40-Thr236). | ||||||||
| Cible | Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein) (Nectican) | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q4VBE4 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Pikachurin (EGFLAM) is a ~110 kDa protein. Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. 1. Sato, S. et al. (2008) Nature neuroscience 11, 923-31. PMID: 18641643 2. Manabe, R. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 12849-54. PMID: 18757743 3. Orlandi, C. et al. (2018) Cell reports 25, 130-145.e5. PMID: 30282023 | ||||||||
| Note | For research use only. |
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