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Anti-Mouse EGFLAM Polyclonal Antibody (MP294014)

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Aperçu
Numéro de catalogueMP294014
Description
Anti-Mouse EGFLAM Polyclonal Antibody (MP294014) is a rabbit polyclonal antibody detecting EGFLAM in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesMouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Mouse EGFLAM (Asp40-Thr236).
Cible Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein) (Nectican)
Purification Purified by antigen affinity column.
Numéro d'accès Q4VBE4
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Pikachurin (EGFLAM) is a ~110 kDa protein. Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness.

1. Sato, S. et al. (2008) Nature neuroscience 11, 923-31. PMID: 18641643
2. Manabe, R. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 12849-54. PMID: 18757743
3. Orlandi, C. et al. (2018) Cell reports 25, 130-145.e5. PMID: 30282023
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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