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| カタログ番号 | MP294014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse EGFLAM Polyclonal Antibody (MP294014) is a rabbit polyclonal antibody detecting EGFLAM in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
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| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse EGFLAM (Asp40-Thr236). | ||||||||
| ターゲット | Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein) (Nectican) | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q4VBE4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Pikachurin (EGFLAM) is a ~110 kDa protein. Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. 1. Sato, S. et al. (2008) Nature neuroscience 11, 923-31. PMID: 18641643 2. Manabe, R. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 12849-54. PMID: 18757743 3. Orlandi, C. et al. (2018) Cell reports 25, 130-145.e5. PMID: 30282023 | ||||||||
| 注意事項 | For research use only. |
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