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Anti-Mouse Erythropoietin R Polyclonal Antibody (MB152014)

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Vista general
Número de catálogoMB152014
Descripción
Anti-Mouse Erythropoietin R Polyclonal Antibody (MB152014) is a rabbit polyclonal antibody detecting EPOR in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesMouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Mouse EPOR (Asp32-Thr243).
Objetivo Erythropoietin receptor (EPO-R)
Purificación Purified by antigen affinity column.
Número de acceso P14753
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

1. D'Andrea, AD. et al. (1989) Cell 57, 277-85. PMID: 2539263
2. Sawyer, ST. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 6849-53. PMID: 8341708
3. Miura, O. et al. (1993) Molecular and cellular biology 13, 1788-95. PMID: 8382775
4. Hilton, DJ. et al. (1996) The Journal of biological chemistry 271, 4699-708. PMID: 8617735
5. Chin, H. et al. (1998) Blood 91, 3734-45. PMID: 9573010
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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