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| カタログ番号 | MB152014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse Erythropoietin R Polyclonal Antibody (MB152014) is a rabbit polyclonal antibody detecting EPOR in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
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| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse EPOR (Asp32-Thr243). | ||||||||
| ターゲット | Erythropoietin receptor (EPO-R) | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P14753 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. 1. D'Andrea, AD. et al. (1989) Cell 57, 277-85. PMID: 2539263 2. Sawyer, ST. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 6849-53. PMID: 8341708 3. Miura, O. et al. (1993) Molecular and cellular biology 13, 1788-95. PMID: 8382775 4. Hilton, DJ. et al. (1996) The Journal of biological chemistry 271, 4699-708. PMID: 8617735 5. Chin, H. et al. (1998) Blood 91, 3734-45. PMID: 9573010 | ||||||||
| 注意事項 | For research use only. |
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