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| カタログ番号 | MX954014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse FABP5 Polyclonal Antibody (MX954014) is a rabbit polyclonal antibody detecting FABP5 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse FABP5 (Met1-Gln135). | ||||||||
| ターゲット | Psoriasis-associated fatty acid-binding protein homolog, FABP5, E-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein, epidermal, Fatty acid-binding protein 5, PA-FABP | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q05816 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Fatty acid-binding protein 5 (FABP5) is a ~15 kDa protein. Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation. 1. Maeda, K. et al. (2003) Diabetes 52, 300-7. PMID: 12540600 2. Kane, CD. et al. (1996) Biochemistry 35, 2894-900. PMID: 8608126 3. Schug, TT. et al. (2007) Cell 129, 723-33. PMID: 17512406 4. Haj-Dahmane, S. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 3482-3487. PMID: 29531087 5. Bogdan, D. et al. (2018) The Journal of biological chemistry 293, 5295-5306. PMID: 29440395 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-FABP5 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse skin lysate
Lane 3: Rat brain lysate
Lane 4: Rat liver lysate
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