

| Número de catálogo | MC591014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Mouse FADD Polyclonal Antibody (MC591014) is a rabbit polyclonal antibody detecting Fadd in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactividad de especies | Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse FADD (Met1-Pro205). | ||||||||
| Objetivo | FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Fadd, Mort1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q61160 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | FAS-associated death domain protein (FADD) is a ~22 kDa protein. Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-FADD polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: A549 cell lysate
Lane 3: HepG2 cell lysate
Lane 4: Jurkat cell lysate
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