

| Numéro de catalogue | MX061014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse FCRN/FCGRT Polyclonal Antibody (MX061014) is a rabbit polyclonal antibody detecting FCRN/FCGRT in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse FCGRT/FCRN (Arg25-Ser292). | ||||||||
| Cible | IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter alpha chain) (Neonatal Fc receptor) | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q61559 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | IgG receptor FcRn large subunit p51 (FCGRT) is a ~40 kDa protein. Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. 1. Ahouse, JJ. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 6076-88. PMID: 7504013 | ||||||||
| Note | For research use only. |
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