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Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22) (MV462013)

Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)
Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)
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Aperçu
Numéro de catalogueMV462013
Description
Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22) (MV462013) is a mouse monoclonal antibody detecting FGF13/FHF2 in FCM, IF, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsFCM, IF, IHC, WB
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneN235/22
Cible FGF13, FHF-2, Fibroblast growth factor homologous factor 2, FGF-13, Fibroblast growth factor 13, FHF2
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P70377
RRID Anti-Mouse FGF13 Antibody (N235/22) (abinScience Cat# MV462013, RRID:AB_3725654)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Fibroblast growth factor 13 (FGF13) is a ~27 kDa protein. Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling.

1. Wu, QF. et al. (2012) Cell 149, 1549-64. PMID: 22726441
2. Wang, C. et al. (2011) Circulation research 109, 775-82. PMID: 21817159
3. Schoorlemmer, J. et al. (2001) Current biology : CB 11, 793-7. PMID: 11378392
4. Schoorlemmer, J. et al. (2002) The Journal of biological chemistry 277, 49111-9. PMID: 12244047
5. Favuzzi, E. et al. (2019) Science (New York, N.Y.) 363, 413-417. PMID: 30679375
Note For research use only.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Images
  • Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse FGF13 Antibody (N235/22).

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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