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| カタログ番号 | MV462013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22) (MV462013) is a mouse monoclonal antibody detecting FGF13/FHF2 in FCM, IF, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||
| アプリケーション | FCM, IF, IHC, WB | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1, kappa | ||||
| クローンID | N235/22 | ||||
| ターゲット | FGF13, FHF-2, Fibroblast growth factor homologous factor 2, FGF-13, Fibroblast growth factor 13, FHF2 | ||||
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P70377 | ||||
| RRID | Anti-Mouse FGF13 Antibody (N235/22) (abinScience Cat# MV462013, RRID:AB_3725654) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Fibroblast growth factor 13 (FGF13) is a ~27 kDa protein. Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. 1. Wu, QF. et al. (2012) Cell 149, 1549-64. PMID: 22726441 2. Wang, C. et al. (2011) Circulation research 109, 775-82. PMID: 21817159 3. Schoorlemmer, J. et al. (2001) Current biology : CB 11, 793-7. PMID: 11378392 4. Schoorlemmer, J. et al. (2002) The Journal of biological chemistry 277, 49111-9. PMID: 12244047 5. Favuzzi, E. et al. (2019) Science (New York, N.Y.) 363, 413-417. PMID: 30679375 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |
SDS-PAGE for Anti-Mouse FGF13 Antibody (N235/22).
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