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Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22) (MV462013)

Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)
Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)
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Спецификация:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Количество:
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Обзор
Каталожный номерMV462013
Описание
Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22) (MV462013) is a mouse monoclonal antibody detecting FGF13/FHF2 in FCM, IF, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Реактивность видовHuman, Mouse, Rat
ПримененияFCM, IF, IHC, WB
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG1, kappa
ID клонаN235/22
Цель FGF13, FHF-2, Fibroblast growth factor homologous factor 2, FGF-13, Fibroblast growth factor 13, FHF2
Уровень эндотоксинов < 10 EU/mg as determined by LAL method.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P70377
RRID Anti-Mouse FGF13 Antibody (N235/22) (abinScience Cat# MV462013, RRID:AB_3725654)
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

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Информация об использовании продукта
Применение Разбавление
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

Fibroblast growth factor 13 (FGF13) is a ~27 kDa protein. Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling.

1. Wu, QF. et al. (2012) Cell 149, 1549-64. PMID: 22726441
2. Wang, C. et al. (2011) Circulation research 109, 775-82. PMID: 21817159
3. Schoorlemmer, J. et al. (2001) Current biology : CB 11, 793-7. PMID: 11378392
4. Schoorlemmer, J. et al. (2002) The Journal of biological chemistry 277, 49111-9. PMID: 12244047
5. Favuzzi, E. et al. (2019) Science (New York, N.Y.) 363, 413-417. PMID: 30679375
Примечание For research use only.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Изображения
  • Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse FGF13 Antibody (N235/22).

Ссылки
Formula
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