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Anti-Mouse FLRT2 Polyclonal Antibody (MT118014)

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Aperçu
Numéro de catalogueMT118014
Description
Anti-Mouse FLRT2 Polyclonal Antibody (MT118014) is a rabbit polyclonal antibody detecting FLRT2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Mouse FLRT2 (Cys36-Ser359).
Cible Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin leucine rich transmembrane protein 2)
Purification Purified by antigen affinity column.
Numéro d'accès Q8BLU0
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Leucine-rich repeat transmembrane protein FLRT2 is a ~73 kDa protein. Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades.

1. Müller, PS. et al. (2011) Development (Cambridge, England) 138, 1297-308. PMID: 21350012
2. Seiradake, E. et al. (2014) Neuron 84, 370-85. PMID: 25374360
3. Jackson, VA. et al. (2015) Structure (London, England : 1993) 23, 774-81. PMID: 25728924
4. Yamagishi, S. et al. (2011) The EMBO journal 30, 2920-33. PMID: 21673655
5. Haines, BP. et al. (2006) Developmental biology 297, 14-25. PMID: 16872596
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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