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| カタログ番号 | MT118014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse FLRT2 Polyclonal Antibody (MT118014) is a rabbit polyclonal antibody detecting FLRT2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse FLRT2 (Cys36-Ser359). | ||||||||
| ターゲット | Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin leucine rich transmembrane protein 2) | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8BLU0 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Leucine-rich repeat transmembrane protein FLRT2 is a ~73 kDa protein. Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. 1. Müller, PS. et al. (2011) Development (Cambridge, England) 138, 1297-308. PMID: 21350012 2. Seiradake, E. et al. (2014) Neuron 84, 370-85. PMID: 25374360 3. Jackson, VA. et al. (2015) Structure (London, England : 1993) 23, 774-81. PMID: 25728924 4. Yamagishi, S. et al. (2011) The EMBO journal 30, 2920-33. PMID: 21673655 5. Haines, BP. et al. (2006) Developmental biology 297, 14-25. PMID: 16872596 | ||||||||
| 注意事項 | For research use only. |
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