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Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII) (MB265107)

Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII)
Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • Datasheet

  • SDS

Vista general
Número de catálogoMB265107
Reactividad de especiesMouse
AplicacionesELISA, FCM
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonAbIII
Objetivo FLT1, Vascular endothelial growth factor receptor 1, VEGFR1, Vascular permeability factor receptor, FRT, Tyrosine-protein kinase receptor FLT, VEGFR-1, FLT, FLT-1, Tyrosine-protein kinase FRT, Fms-like tyrosine kinase 1
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P35969
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~149 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific.

1. Nguyen, MT. et al. (2019) Nature cell biology 21, 420-429. PMID: 30936473
Nota For research use only.
Imágenes
  • Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse FLT1/VEGFR1 Antibody (AbIII)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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