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Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII) (MB265107)

Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII)
Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII)
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  • 100ug
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Aperçu
Numéro de catalogueMB265107
Reactivité des espècesMouse
ApplicationsELISA, FCM
Espèce hôteRat
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneAbIII
Cible FLT1, Vascular endothelial growth factor receptor 1, VEGFR1, Vascular permeability factor receptor, FRT, Tyrosine-protein kinase receptor FLT, VEGFR-1, FLT, FLT-1, Tyrosine-protein kinase FRT, Fms-like tyrosine kinase 1
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P35969
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~149 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific.

1. Nguyen, MT. et al. (2019) Nature cell biology 21, 420-429. PMID: 30936473
Note For research use only.
Images
  • Anti-Mouse VEGFR1/Flt-1 Recombinant Antibody (AbIII)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse FLT1/VEGFR1 Antibody (AbIII)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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