

| Número de catálogo | MC526014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Mouse FZD5 Polyclonal Antibody (MC526014) is a rabbit polyclonal antibody detecting FZD5 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse FZD5 (Thr37-Ala126). | ||||||||
| Objetivo | Frizzled-5, FzE5, C2orf31, hFz5, FZD5, Fz-5 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9EQD0 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Frizzled-5 (FZD5) is a ~64 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling. In neurons, activation by WNT7A promotes formation of synapses. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). 1. Ishikawa, T. et al. (2001) Development (Cambridge, England) 128, 25-33. PMID: 11092808 2. Carmon, KS. et al. (2008) Biochemical and biophysical research communications 368, 285-91. PMID: 18230341 | ||||||||
| Nota | For research use only. |
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