Anti-Mouse GATA4 Polyclonal Antibody (MW583014)

Name: Anti-Mouse GATA4 Polyclonal Antibody
Brand: abinScience
SKU: MW583014
Price: 96 USD
Availability: InStock

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Datasheet
SDS

Vista general

Número de catálogo

MW583014

Descripción

Anti-Mouse GATA4 Polyclonal Antibody (MW583014) is a rabbit polyclonal antibody detecting Gata4 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Mouse GATA4 (Leu204-Ile314).

Objetivo

Transcription factor GATA-4, GATA-binding factor 4, Gata4, Gata-4

Purificación

Purified by antigen affinity column.

Número de acceso

Q08369

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Transcription factor GATA-4 (GATA4) is a ~44 kDa protein. Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it down-regulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5.

1. Garry, GA. et al. (2021) Nature cell biology 23, 467-475. PMID: 33941892

2. Gonzalez-Teran, B. et al. (2022) Cell 185, 794-814.e30. PMID: 35182466

3. Lee, Y. et al. (1998) Molecular and cellular biology 18, 3120-9. PMID: 9584153

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Mouse GATA4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo