中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | MW583014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse GATA4 Polyclonal Antibody (MW583014) is a rabbit polyclonal antibody detecting Gata4 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
|
||||||||
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse GATA4 (Leu204-Ile314). | ||||||||
| ターゲット | Transcription factor GATA-4, GATA-binding factor 4, Gata4, Gata-4 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q08369 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Transcription factor GATA-4 (GATA4) is a ~44 kDa protein. Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it down-regulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. 1. Garry, GA. et al. (2021) Nature cell biology 23, 467-475. PMID: 33941892 2. Gonzalez-Teran, B. et al. (2022) Cell 185, 794-814.e30. PMID: 35182466 3. Lee, Y. et al. (1998) Molecular and cellular biology 18, 3120-9. PMID: 9584153 | ||||||||
| 注意事項 | For research use only. |
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
