Anti-Mouse Glypican 3 Recombinant Antibody (7C8) (MW310013)

Name: Anti-Mouse Glypican 3 Recombinant Antibody (7C8)
Brand: abinScience
SKU: MW310013
Price: 126 USD
Availability: InStock

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Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

MW310013

Реактивность видов

Mouse

Применения

Blocking, ELISA, FCM

Хозяинский вид

Rat

Клоональность

Monoclonal

Изотип

IgG1

ID клона

7C8

Проверенные приложения

Цель

GPC3, MXR7, GTR2-2, Glypican-3, Intestinal protein OCI-5, OCI5

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q8CFZ4

RRID

Anti-Mouse GPC3 Antibody (7C8) (abinScience Cat# MW310013, RRID:AB_3725638)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Glypican-3 (GPC3/Glypican 3) is a ~65 kDa protein. Cell surface proteoglycan. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway.

1. Capurro, MI. et al. (2008) Developmental cell 14, 700-11. PMID: 18477453

2. Bhave, VS. et al. (2013) The American journal of pathology 183, 153-9. PMID: 23665349

3. Song, HH. et al. (2005) The Journal of biological chemistry 280, 2116-25. PMID: 15537637

4. Paine-Saunders, S. et al. (2000) Developmental biology 225, 179-87. PMID: 10964473

5. Grisaru, S. et al. (2001) Developmental biology 231, 31-46. PMID: 11180950

6. Ng, A. et al. (2009) Developmental biology 335, 208-15. PMID: 19733558

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Mouse GPC3 Antibody (7C8).
Western blot

Lane 1: HepG2 cell lysate

Ссылки

Даташит

Anti-Mouse Glypican 3 Recombinant Antibody (7C8).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа