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| カタログ番号 | MY365014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse GPX1 Polyclonal Antibody (MY365014) is a rabbit polyclonal antibody detecting Gpx1 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse GPX1 (Gly48-Ser201). | ||||||||
| ターゲット | Glutathione peroxidase 1, GPx-1, GSHPx-1, 1.11.1.9, Cellular glutathione peroxidase, Phospholipid-hydroperoxide glutathione peroxidase GPX1, 1.11.1.12, Selenium-dependent glutathione peroxidase 1, Gpx1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11352 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutathione peroxidase 1 (GPX1) is a ~22 kDa protein. Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway. 1. Esposito, LA. et al. (2000) Free radical biology & medicine 28, 754-66. PMID: 10754271 2. Wang, SK. et al. (2011) Free radical biology & medicine 51, 197-204. PMID: 21420488 3. Schwarz, M. et al. (2023) Redox biology 59, 102593. PMID: 36608588 4. Esworthy, RS. et al. (1997) Archives of biochemistry and biophysics 340, 59-63. PMID: 9126277 5. Ho, YS. et al. (1997) The Journal of biological chemistry 272, 16644-51. PMID: 9195979 6. de Haan, JB. et al. (1998) The Journal of biological chemistry 273, 22528-36. PMID: 9712879 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-GPX1 polyclonal antibody at GPX1 on various samples.
Lane 1: Mouse liver lysate
Lane 2: Mouse kidney lysate
Lane 3: Mouse spleen lysate
Lane 4: Mouse lung lysate
Lane 5: Rat liver lysate
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