

| Numéro de catalogue | MV476014 | ||||||||
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| Description |
Anti-Mouse HDAC9 Polyclonal Antibody (MV476014) is a rabbit polyclonal antibody detecting Hdac9 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse HDAC9 (Val37-Pro161). | ||||||||
| Cible | Histone deacetylase 9, HD9, 3.5.1.98, Histone deacetylase 7B, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, Hdac9, Hdac7b, Hdrp, Mitr | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q99N13 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Histone deacetylase 9 (HDAC9) is a ~65 kDa protein. Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting HDAC1 and HDAC3. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription, inhibits skeletal myogenesis and may be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter. | ||||||||
| Note | For research use only. |
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