

| Каталожный номер | MV476014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Mouse HDAC9 Polyclonal Antibody (MV476014) is a rabbit polyclonal antibody detecting Hdac9 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Mouse HDAC9 (Val37-Pro161). | ||||||||
| Цель | Histone deacetylase 9, HD9, 3.5.1.98, Histone deacetylase 7B, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, Hdac9, Hdac7b, Hdrp, Mitr | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q99N13 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Histone deacetylase 9 (HDAC9) is a ~65 kDa protein. Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting HDAC1 and HDAC3. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription, inhibits skeletal myogenesis and may be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter. | ||||||||
| Примечание | For research use only. |
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