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| カタログ番号 | MX030014 | ||||||||
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| 説明 |
Anti-Mouse HSPG2 Polyclonal Antibody (MX030014) is a rabbit polyclonal antibody detecting HSPG2 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse HSPG2 (Asp4190-Ser4383). | ||||||||
| ターゲット | Perlecan (heparan sulfate proteoglycan 2), Hspg2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | E9PZ16 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2) is a ~469 kDa protein. Anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6. | ||||||||
| 注意事項 | For research use only. |
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