Anti-Mouse ST2/IL-33R Polyclonal Antibody (MX139014)

Name: Anti-Mouse ST2/IL-33R Polyclonal Antibody
Brand: abinScience
SKU: MX139014
Price: 96 USD
Availability: InStock

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

MX139014

Реактивность видов

Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Mouse IL1RL1/ST2 (Ser27-Arg332).

Проверенные приложения

Цель

Interleukin-1 receptor-like 1 (EC 3.2.2.6) (Interleukin-33 receptor alpha chain) (Lymphocyte antigen 84) (Protein ST2) (Protein T1)

Очистка

Purified by antigen affinity column.

Номер доступа

P14719

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Interleukin-1 receptor-like 1 (IL1RL1/ST2) is a ~64 kDa protein. Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages.

1. Chackerian, AA. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 2551-5. PMID: 17675517

2. Palmer, G. et al. (2008) Cytokine 42, 358-64. PMID: 18450470

3. Zhao, J. et al. (2012) Nature immunology 13, 651-8. PMID: 22660580

4. Osbourn, M. et al. (2017) Immunity 47, 739-751.e5. PMID: 29045903

5. Faas, M. et al. (2021) Immunity 54, 2531-2546.e5. PMID: 34644537

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-IL1RL1 polyclonal antibody at 1µg/ml on various samples.
Lane 1: Hela cell lysate
Lane 2: SGC-7901 cell lysate
Lane 3: HUVEC cell lysate
Lane 4: HepG2 cell lysate
Lane 5: Mouse brain lysate

Ссылки

Даташит

Anti-Mouse ST2/IL-33R Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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