

| Numéro de catalogue | MV045014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse IL1RL2/IL-36R Polyclonal Antibody (MV045014) is a rabbit polyclonal antibody detecting IL-36R in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse IL1RL2/IL-36R (Met29-Ile331). | ||||||||
| Cible | IL1R-rp2, IL1RL2, IL1RRP2, IL-1Rrp2, IL-36 receptor, Interleukin-1 receptor-related protein 2, Interleukin-1 receptor-like 2, IL-36R | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9ERS7 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Interleukin-1 receptor-like 2 (IL1RL2/IL-36R) is a ~65 kDa protein. Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-IL1RL2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: HL-60 cell lysate



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