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Anti-Mouse IL-21 Polyclonal Antibody (MV658014)

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Vista general
Número de catálogoMV658014
Descripción
Anti-Mouse IL21 Polyclonal Antibody (MV658014) is a rabbit polyclonal antibody detecting IL21 in ELISA, IHC, WB. Suitable for Rattus norvegicus and Mus musculus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesMouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Mouse IL21 (Pro25-Ser146).
Objetivo IL21
Purificación Purified by antigen affinity column.
Número de acceso Q9ES17
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosInterleukin-21, IL-21, Il21
Fondo

Interleukin-21 (IL21) is a ~16 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.

1. Pène, J. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 5154-7. PMID: 15100251
2. Karnowski, A. et al. (2012) The Journal of experimental medicine 209, 2049-64. PMID: 23045607
3. Kasaian, MT. et al. (2002) Immunity 16, 559-69. PMID: 11970879
4. Brandt, K. et al. (2003) Blood 102, 4090-8. PMID: 12893770
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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