

| Numéro de catalogue | MV658014 | ||||||||
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| Description |
Anti-Mouse IL21 Polyclonal Antibody (MV658014) is a rabbit polyclonal antibody detecting IL21 in ELISA, IHC, WB. Suitable for Rattus norvegicus and Mus musculus.
Highlights
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse IL21 (Pro25-Ser146). | ||||||||
| Cible | IL21 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9ES17 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Noms alternatifs | Interleukin-21, IL-21, Il21 | ||||||||
| Contexte | Interleukin-21 (IL21) is a ~16 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Pène, J. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 5154-7. PMID: 15100251 2. Karnowski, A. et al. (2012) The Journal of experimental medicine 209, 2049-64. PMID: 23045607 3. Kasaian, MT. et al. (2002) Immunity 16, 559-69. PMID: 11970879 4. Brandt, K. et al. (2003) Blood 102, 4090-8. PMID: 12893770 | ||||||||
| Note | For research use only. |
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