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Anti-Mouse IL-21 Polyclonal Antibody (MV658014)

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Aperçu
Numéro de catalogueMV658014
Description
Anti-Mouse IL21 Polyclonal Antibody (MV658014) is a rabbit polyclonal antibody detecting IL21 in ELISA, IHC, WB. Suitable for Rattus norvegicus and Mus musculus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesMouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Mouse IL21 (Pro25-Ser146).
Cible IL21
Purification Purified by antigen affinity column.
Numéro d'accès Q9ES17
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsInterleukin-21, IL-21, Il21
Contexte

Interleukin-21 (IL21) is a ~16 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.

1. Pène, J. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 5154-7. PMID: 15100251
2. Karnowski, A. et al. (2012) The Journal of experimental medicine 209, 2049-64. PMID: 23045607
3. Kasaian, MT. et al. (2002) Immunity 16, 559-69. PMID: 11970879
4. Brandt, K. et al. (2003) Blood 102, 4090-8. PMID: 12893770
Note For research use only.
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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