

| Numéro de catalogue | MV678014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse IL31 Polyclonal Antibody (MV678014) is a rabbit polyclonal antibody detecting IL-31 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse IL31 (Ala31-Cys163). | ||||||||
| Applications testées | WB | ||||||||
| Cible | Interleukin-31 (IL-31) | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6EAL8 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Interleukin-31 (IL31) is a ~18 kDa protein. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro. Induces RETNLA and serum amyloid A protein expression in macrophages. 1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896 2. Broxmeyer, HE. et al. (2007) Experimental hematology 35, 78-86. PMID: 17379091 3. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-IL31 polyclonal antibody at 1µg/ml on various samples.
Lane 1: RAW264.7 cell lysate
Lane 2: Mouse lung lysate
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