Anti-Mouse IL-5 Polyclonal Antibody (MY218014)

Name: Anti-Mouse IL-5 Polyclonal Antibody
Brand: abinScience
SKU: MY218014
Price: 168 USD
Availability: InStock

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Даташит
SDS

Обзор

Каталожный номер

MY218014

Описание

Anti-Mouse IL5 Polyclonal Antibody (MY218014) is a rabbit polyclonal antibody detecting Il5. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Mouse IL5 (Met21-Gly133).

Цель

B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, IL-5, Il-5, Il5, Interleukin-5, T-cell replacing factor, TRF

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P04401

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Фон

Interleukin-5 (IL5) is a ~15 kDa protein. Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively. IL5 is the therapeutic target of mepolizumab (Nucala).

1. Vallance, BA. et al. (1999) The American journal of physiology 277, G400-8. PMID: 10444455

2. Barry, SC. et al. (1991) Cytokine 3, 339-44. PMID: 1873482

3. Karasuyama, H. et al. (1988) The Journal of experimental medicine 167, 1377-90. PMID: 3128631

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Mouse IL-5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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