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| カタログ番号 | MC068014 | ||||||||
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| 説明 |
Anti-Mouse LHFPL5 Polyclonal Antibody (MC068014) is a rabbit polyclonal antibody detecting LHFPL tetraspan subfamily member 5 protein isoform X2; Lhfpl5 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant mouse LHFPL5 (Ile50-Met98&Asp150-Arg176&Arg202-Val219). | ||||||||
| ターゲット | LHFPL tetraspan subfamily member 5 protein isoform X2; Lhfpl5 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q4KL25 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | LHFPL tetraspan subfamily member 5 protein (LHFPL5) is a ~24 kDa protein. Auxiliary subunit of the mechanotransducer (MET) non-specific cation channel complex located at the tips of the shorter stereocilia of cochlear hair cells and that mediates sensory transduction in the auditory system. The MET complex is composed of two dimeric pore-forming ion-conducting transmembrane TMC (TMC1 or TMC2) subunits, and aided by several auxiliary proteins including LHFPL5, TMIE, CIB2/3 and TOMT, and the tip-link PCDH15. Functionally couples PCDH15 to the transduction channel. 1. Longo-Guess, CM. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 7894-9. PMID: 15905332 2. Xiong, W. et al. (2012) Cell 151, 1283-95. PMID: 23217710 3. Fettiplace, R. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2210849119. PMID: 36191207 | ||||||||
| 注意事項 | For research use only |
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