Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), FITC (MS714117)

Name: Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), FITC
Brand: abinScience
SKU: MS714117
Price: 223 USD
Availability: InStock

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概要

カタログ番号	MS714117
種反応性	Human, Mouse
アプリケーション	FCM
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG2a, kappa
クローンID	SAA1998
抱合	FITC
ターゲット	SCA-2, TSA-1, 9804, Retinoic acid-induced gene E protein, TSA1, Lymphocyte antigen 6E, Ly-6E, Stem cell antigen 2, Thymic shared antigen 1, SCA2, RIGE, LY6E, RIG-E
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
アクセッション番号	Q64253
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Lymphocyte antigen 6E (LY6E/SCA-2) is a ~14 kDa protein. GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of murine coronavirus, mouse hepatitis virus, by interfering with spike protein-mediated membrane fusion. Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. 1. Noda, S. et al. (1996) The Journal of experimental medicine 183, 2355-60. PMID: 8642345 2. Kosugi, A. et al. (1998) The Journal of biological chemistry 273, 12301-6. PMID: 9575182 3. Pfaender, S. et al. (2020) Nature microbiology 5, 1330-1339. PMID: 32704094 4. Bacquin, A. et al. (2017) Journal of virology 91. PMID: 28679758 5. Langford, MB. et al. (2018) Scientific reports 8, 3961. PMID: 29500366 6. Wu, M. et al. (2015) The Journal of biological chemistry 290, 24509-18. PMID: 26276394
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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データシート

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), FITC.pdf

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Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), FITC (MS714117)

概要

イメージ

参考文献

データシート

SDS

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