Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998) (MS714107)

Name: Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998)
Brand: abinScience
SKU: MS714107
Price: 191 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MS714107

Reactivité des espèces

Human, Mouse

Applications

FCM, WB

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1998

Cible

SCA-2, TSA-1, 9804, Retinoic acid-induced gene E protein, TSA1, Lymphocyte antigen 6E, Ly-6E, Stem cell antigen 2, Thymic shared antigen 1, SCA2, RIGE, LY6E, RIG-E

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q64253

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Lymphocyte antigen 6E (LY6E/SCA-2) is a ~14 kDa protein. GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of murine coronavirus, mouse hepatitis virus, by interfering with spike protein-mediated membrane fusion. Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta.

1. Noda, S. et al. (1996) The Journal of experimental medicine 183, 2355-60. PMID: 8642345

2. Kosugi, A. et al. (1998) The Journal of biological chemistry 273, 12301-6. PMID: 9575182

3. Pfaender, S. et al. (2020) Nature microbiology 5, 1330-1339. PMID: 32704094

4. Bacquin, A. et al. (2017) Journal of virology 91. PMID: 28679758

5. Langford, MB. et al. (2018) Scientific reports 8, 3961. PMID: 29500366

6. Wu, M. et al. (2015) The Journal of biological chemistry 290, 24509-18. PMID: 26276394

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-LY6E/SCA-2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 50ng
Lane 2: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 30ng
Lane 3: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 20ng
Lane 4: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 10ng
SDS-PAGE

SDS-PAGE for Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998)

Reférences

Fiche technique

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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