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Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014)

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Vista general
Número de catálogoMB964014
Descripción
Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014) is a rabbit polyclonal antibody detecting Midkine. Suitable for Mouse and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesMouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Mouse MDK/Midkine (Lys23-Asp140).
Objetivo MK, Mdk, Midkine, Mk, Retanoic acid-responsive protein, Retinoic acid-induced differentiation factor
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P12025
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Midkine (MDK) is a ~15 kDa protein. Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression.

1. Ichihara-Tanaka, K. et al. (2006) The Journal of biological chemistry 281, 30857-64. PMID: 16901907
2. Zou, P. et al. (2006) Journal of neurochemistry 99, 1470-9. PMID: 17230638
3. Horiba, M. et al. (2000) The Journal of clinical investigation 105, 489-95. PMID: 10683378
4. Ochiai, K. et al. (2004) Liver international : official journal of the International Association for the Study of the Liver 24, 484-91. PMID: 15482347
5. Kawai, H. et al. (2004) The American journal of pathology 165, 1603-12. PMID: 15509530
6. Horiba, M. et al. (2006) Circulation 114, 1713-20. PMID: 17015789
7. Takenaka, H. et al. (2009) American journal of physiology. Heart and circulatory physiology 296, H462-9. PMID: 19060126
8. Weckbach, LT. et al. (2014) Blood 123, 1887-96. PMID: 24458438
9. Haffner-Luntzer, M. et al. (2014) PloS one 9, e116282. PMID: 25551381
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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