Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014)

Name: Anti-Mouse MDK/Midkine Polyclonal Antibody
Brand: abinScience
SKU: MB964014
Price: 168 USD
Availability: InStock

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100ug

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MB964014

Description

Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014) is a rabbit polyclonal antibody detecting Midkine. Suitable for Mouse and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Mouse MDK/Midkine (Lys23-Asp140).

Cible

MK, Mdk, Midkine, Mk, Retanoic acid-responsive protein, Retinoic acid-induced differentiation factor

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P12025

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Midkine (MDK) is a ~15 kDa protein. Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression.

1. Ichihara-Tanaka, K. et al. (2006) The Journal of biological chemistry 281, 30857-64. PMID: 16901907

2. Zou, P. et al. (2006) Journal of neurochemistry 99, 1470-9. PMID: 17230638

3. Horiba, M. et al. (2000) The Journal of clinical investigation 105, 489-95. PMID: 10683378

4. Ochiai, K. et al. (2004) Liver international : official journal of the International Association for the Study of the Liver 24, 484-91. PMID: 15482347

5. Kawai, H. et al. (2004) The American journal of pathology 165, 1603-12. PMID: 15509530

6. Horiba, M. et al. (2006) Circulation 114, 1713-20. PMID: 17015789

7. Takenaka, H. et al. (2009) American journal of physiology. Heart and circulatory physiology 296, H462-9. PMID: 19060126

8. Weckbach, LT. et al. (2014) Blood 123, 1887-96. PMID: 24458438

9. Haffner-Luntzer, M. et al. (2014) PloS one 9, e116282. PMID: 25551381

Note

For research use only

Images

Reférences

Fiche technique

Anti-Mouse MDK/Midkine Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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