中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | MB964014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014) is a rabbit polyclonal antibody detecting Midkine. Suitable for Mouse and Rat.
Highlights
|
||||||||
| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse MDK/Midkine (Lys23-Asp140). | ||||||||
| ターゲット | MK, Mdk, Midkine, Mk, Retanoic acid-responsive protein, Retinoic acid-induced differentiation factor | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P12025 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 背景 | Midkine (MDK) is a ~15 kDa protein. Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression. 1. Ichihara-Tanaka, K. et al. (2006) The Journal of biological chemistry 281, 30857-64. PMID: 16901907 2. Zou, P. et al. (2006) Journal of neurochemistry 99, 1470-9. PMID: 17230638 3. Horiba, M. et al. (2000) The Journal of clinical investigation 105, 489-95. PMID: 10683378 4. Ochiai, K. et al. (2004) Liver international : official journal of the International Association for the Study of the Liver 24, 484-91. PMID: 15482347 5. Kawai, H. et al. (2004) The American journal of pathology 165, 1603-12. PMID: 15509530 6. Horiba, M. et al. (2006) Circulation 114, 1713-20. PMID: 17015789 7. Takenaka, H. et al. (2009) American journal of physiology. Heart and circulatory physiology 296, H462-9. PMID: 19060126 8. Weckbach, LT. et al. (2014) Blood 123, 1887-96. PMID: 24458438 9. Haffner-Luntzer, M. et al. (2014) PloS one 9, e116282. PMID: 25551381 | ||||||||
| 注意事項 | For research use only |
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
