Anti-Mouse MMP3 Recombinant Antibody (CH01) (MY526013)

Name: Anti-Mouse MMP3 Recombinant Antibody (CH01)
Brand: abinScience
SKU: MY526013
Price: 110 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MY526013

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IF

Especie huésped

Rat

Clonalidad

Monoclonal

Isotipo

IgG1, kappa

ID de clon

CH01

Objetivo

SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P28862

RRID

Anti-Mouse MMP3 Antibody (CH01) (abinScience Cat# MY526013, RRID:AB_3725632)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Stromelysin-1 (MMP3) is a ~53 kDa protein. Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. Also acts intracellularly. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage.

1. Kim, YS. et al. (2007) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21, 179-87. PMID: 17116747

2. Feng, T. et al. (2022) Antiviral research 206, 105388. PMID: 35940311

Nota

For research use only.

Isotype Control

Rat IgG1, kappa Recombinant Isotype Control Antibody (RTK2071) (RV080407)

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Mouse MMP3 Antibody (CH01)
Bioactivity

Detects recombinant human MMP3 (Catalog No: HY526012) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human MMP3 antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human MMP3 monoclonal antibody (Catalog MY526013, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Rat IgG H&L Polyclonal Antibody, FITC (abinScience: RF690334) and cells analysed on a NovoCyte Flow Cytometer.

Referencias

Datasheet

Anti-Mouse MMP3 Recombinant Antibody (CH01).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo