

| Numéro de catalogue | MY413014 | ||||||||
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| Description |
Anti-Mouse MPO Polyclonal Antibody (MY413014) is a rabbit polyclonal antibody detecting MPO. Suitable for Mouse.
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse MPO (Ser289-Thr718). | ||||||||
| Cible | EC:1.11.2.2, MPO, Mpo, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P11247 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Myeloperoxidase (MPO) is a ~81 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low density lipoprotein particles and limits vascular damage. 1. Gaut, JP. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 11961-6. PMID: 11593004 | ||||||||
| Note | For research use only |


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